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KMID : 1134820140430101588
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Journal of the Korean Society of Food Science and Nutrition
2014 Volume.43 No. 10 p.1588 ~ p.1593
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Genotoxicological Safety Evaluation of X-ray Irradiated Four Foods
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Jung Da-Woon
Huang Yu-Hua
Song Beom-Seok
Byun Myung-Woo
Kang Il-Jun
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Abstract
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This study evaluated the genotoxic effects of 30 kGy of X-ray irradiation to four foods (chicken, egg powder, dried green onion, and black pepper). In bacterial reversion assay with Salmonella Typhimurium TA98, TA100, TA1535, and TA1537, the X-ray irradiated foods did not show a significantly increased number of revertant colonies in the presence or absence of the S9 metabolic activation system. In chromosomal aberration tests with Chinese hamster ovary (CHO) cells, the X-ray irradiated foods showed no increase in the frequency of chromosomal aberrations. In in vivo mouse micronucleus assay, the X-ray irradiated foods did not show any increase in the frequency of polychromatic erythrocytes with micronuclei. These results indicate that 30 kGy of X-ray irradiation to four foods (chicken, egg powder, dried green onion, and black pepper) showed no genotoxic effects under these experimental conditions.
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KEYWORD
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genotoxicity, X-ray irradiated food, bacterial reversion assay, chromosomal aberration test, micronucleus assay
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